Replacement of the 3'-CH group by nitrogen in the carbocyclic analogue of thymidine

Article abstract of DOI:10.1021/jm00128a015

We have prepared (4R)-4-thyminyl-D-prolinol, and the analogue of 3'-deoxythymidine in which sugar has been replaced by D-prolinol. This strongly basic secondary amine has been converted to the corresponding hydroxylamine, an analogue of either thymidine o