Synthesis of N-Substituted Pyrroles From Azlactones via 1,3-Oxazolium 5-Oxides

DOI: 10.1055/s-1988-27785

Source and publish data:

Synthesis p. 999 - 1001 (1988)

Update date:2022-07-29

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Authors:

Hershenson, Fred. M.

Pavia, Michael R.

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Article abstract of DOI:10.1055/s-1988-27785

In situ N-alkylation of azlactones (1,3-oxazol-5(4H)-ones) with reactive alkylating agents has been successfully accomplished.The resulting mesoionic 1,3-oxazolium 5-oxides (munchnones) are further transformed into N-alkylated pyrroles via a 1,3-dipolar c

Full text of DOI:10.1055/s-1988-27785

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