Synthesis of N-Substituted Pyrroles From Azlactones via 1,3-Oxazolium 5-Oxides

Article abstract of DOI:10.1055/s-1988-27785

In situ N-alkylation of azlactones (1,3-oxazol-5(4H)-ones) with reactive alkylating agents has been successfully accomplished.The resulting mesoionic 1,3-oxazolium 5-oxides (munchnones) are further transformed into N-alkylated pyrroles via a 1,3-dipolar c