Synthesis of structurally simplified analogues of aplidinone A, a pro-apoptotic marine thiazinoquinone

DOI: 10.1016/j.bmc.2009.11.063

Source and publish data:

Bioorganic and Medicinal Chemistry p. 719 - 727 (2010)

Update date:2022-08-05

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Authors:

Aiello, Anna

Fattorusso, Ernesto

Luciano, Paolo

Menna, Marialuisa

Calzado, Marco A.

Mu?oz, Eduardo

Bonadies, Francesco

Guiso, Marcella

Sanasi, Maria Filomena

Cocco, Gianfranco

Nicoletti, Rosario

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Article abstract of DOI:10.1016/j.bmc.2009.11.063

The synthesis of analogues of aplidinone A (7), a prenylated quinone isolated from the Mediterranean ascidian Aplidium conicum, has been performed. This work not only allowed confirming the structural assignment of aplidinone A, previously made with the s

Full text of DOI:10.1016/j.bmc.2009.11.063

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