
Journal of Medicinal Chemistry p. 2493 - 2502 (1989)
Update date:2022-08-03
Topics:
Wrobel, Jay
Millen, Jane
Sredy, Janet
Dietrich, Arlene
Kelly, Joseph M.
et al.
A series of aldose reductase inhibitors was prepared in which structural modifications were made to three positions of the potent, orally active inhibitor tolrestat (1), namely, the 6-methoxy substituent, thioamide sulfur, and the N-methyl moiety.These co
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