APPLICATION OF REDUCTIVE, SINGLE ELECTRON TRANSFER PROCESSES TO THE GENERATION AND CYCLIZATION OF ω-UNSATURATED α-AMINO RADICALS

Article abstract of DOI:10.1016/S0040-4039(00)82428-4

Subjection of ω-unsaturated iminium salts 1 to dissolving metal reduction with samarium diiodide in the presence of camphorsulfonic acid afforded the corresponding α-amino radicals 2, which underwent facile cyclization via a 5-exo mode of closure leading