Synthetic Communications p. 237 - 244 (2014)
Update date:2022-08-04
Topics:
Atamanyuk, Dmytro
Zimenkovsky, Borys
Atamanyuk, Vasyl
Lesyk, Roman
5-Ethoxymethylidene-4-thioxo-2-thiazolidinone was studied as versatile core building block in the synthesis of new thiopyrano[2,3-d]thiazole derivatives relevant for medicinal chemistry purposes under hetero-Diels-Alder reaction conditions. Promising compounds (6, 10) were identified among synthesized series with high antitumor and moderate antiviral activity. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for the following free supplemental resource(s): Full experimental and spectral details.]
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