Biphenylcarboxamide derivatives as antagonists of platelet-activating factor

DOI: 10.1021/jm00128a025

Source and publish data:

Journal of Medicinal Chemistry p. 1814 - 1820 (1989)

Update date:2022-07-30

Topics:

Authors:

Tilley Tilley

Clader Clader

Zawoiski

Wirkus Wirkus

LeMahieu

O'Donnell

Crowley Crowley

Welton Welton

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00128a025

A series of N-[4-(3-pyridinyl)butyl]-1,1'-biphenyl-4-carboxamides was prepared, and the compounds were evaluated for platelet-activating factor (PAF) antagonist activity in a binding assay employing washed, whole dog platelets and in vivo for their abilit

Full text of DOI:10.1021/jm00128a025

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Product name:3'-(phenylmethoxy)-N-<4-(3-pyridinyl)butyl>-1,1'-biphenyl-4-carboxamide

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