Journal of Organic Chemistry p. 4649 - 4653 (1989)
Update date:2022-08-03
Topics:
Wieber, Gary M.
Hegedus, Louis S.
Akermark, Bjoern
Michalson, Erik T.
Alkylation of benzyl vinylcarbamate with sodium benzyl acetoacetate in the presence of palladium(II) chloride, followed by carbonylation (CO/MeOH), produced a highly functionalized β-amido ester that was converted, using conventional organic synthetic methodology, into a relay to (+/-)-thienamycin.
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Doi:10.1021/ja00202a054
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