Topologically Constrained Bifunctional Intercalators: DNA Intercalation by a Macrocyclic Bisacridine

DOI: 10.1021/ja00199a047

Source and publish data:

Journal of the American Chemical Society p. 6805 - 6809 (1989)

Update date:2022-09-26

Topics:

Authors:

Zimmerman, Steven C.

Lamberson, Carol R.

Cory, Michael

Fairley, Terri A.

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Article abstract of DOI:10.1021/ja00199a047

A topologically novel DNA bifunctional intercalator, 4, has been synthesized and its DNA binding compared with the binding of the monointercalator 9-aminoacridine (6) and spermine bisacridine (5), a known bisintercalator.Water-soluble macrocyclic bisacrid

Full text of DOI:10.1021/ja00199a047

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