Topologically Constrained Bifunctional Intercalators: DNA Intercalation by a Macrocyclic Bisacridine

DOI: 10.1021/ja00199a047

Source and publish data:

Journal of the American Chemical Society p. 6805 - 6809 (1989)

Update date:2022-09-26

Topics:

Authors:

Zimmerman, Steven C.

Lamberson, Carol R.

Cory, Michael

Fairley, Terri A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00199a047

A topologically novel DNA bifunctional intercalator, 4, has been synthesized and its DNA binding compared with the binding of the monointercalator 9-aminoacridine (6) and spermine bisacridine (5), a known bisintercalator.Water-soluble macrocyclic bisacrid

Full text of DOI:10.1021/ja00199a047

Products guided by the article

Product name:N,N'-Bis<2-<<(9-phenoxyacridin-4-yl)methyl>thio>ethyl>butane-1,4-diamide

Cas No:122313-75-1

R&D Labs maybe for 122313-75-1

Wuhan Sunrise Pharmaceutical Technology Co., Ltd

Contact:+86-27-83314682

Address:Room 340, New material Industrial base No.17, Gu Tian Five Lu , Qiaokou District, Wuhan , China
Shanghai Standard Biotech Co., Ltd.

Contact:+86-18502101150

Address:Room 103, Building 2nd, NO.720, Cailun Road , Pudong District, Shanghai, China
Shijiazhuang Frontierchem Co., Ltd.

Contact:+86-311-89271196

Address:4-4-202 No.15 Biandian Street,Shijiazhuang
Ningbo Huajia Chemicals

Contact:+86-574-87065746

Address:10th Floor, No.787 Baizhang East Road,
Chengdu Baishixing Science and Technology Industry Co., Ltd.

website:http://www.cd-bsx.com

Contact:+86-28-88531548

Address:#217,North of Industry Road,Heshan Town,Pujiang County,Chengdu,Sichuan,China.

Relevant to this article

Metal-free oxidative cyclization of acetophenones with diamines: A facile access to phenylpyridines

Doi:10.1039/c5cc08498a
(2016)
The synthesis and characterization of metal-free and metallophthalocyanine polymers by microwave irradiation containing diazadithia macrocyclic moieties

Doi:10.1016/j.dyepig.2009.10.021
(2010)
Reversal of enantioselectivity by tuning the conformational flexibility of phase-transfer catalysts

Doi:10.1002/anie.200906814
(2010)
Design of peptide hydroxamate-based photoreactive activity-based probes of zinc-dependent metalloproteases

Doi:10.1002/ejoc.200901385
(2010)
Syntheses of new heterocycles derived from 2-phenyl-3,1-benzoxazin-4-one and their antibacterial and antifungal activity

Doi:10.1515/HC.2009.15.4.251
(2009)
Synthesis of heterocycles by intramolecular nucleophilic substitution at an electron-deficient sp² nitrogen atom

Doi:10.1002/ejoc.200901520
(2010)

Article Doi