Phenanthrylalkanoic acids, III: Syntheses and biological activities of 4-phenanthryl derivatives.

DOI: 10.1002/ardp.19893220508

Source and publish data:

Archiv der Pharmazie p. 281 - 284 (1989)

Update date:2022-08-02

Topics:

Authors:

Eirin Eirin

Fernandez

Gomez Gomez

Lopez Lopez

Santos Santos

Calleja Calleja

Cano Cano

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/ardp.19893220508

Reformatsky reactions between 2,3-dihydro-4(1H)-phenanthrenone (5) and ethyl alpha-bromoacetate or propanoate yield several unsaturated esters which, upon aromatization followed by saponification, lead to the 4-phenanthrylacetic (1) and 2-(4-phenanthryl)propanoic (2) acids. The analgesic and anti-inflammatory properties of 1 and 2 were measured and compared with those of Fenbufen.

Full text of DOI:10.1002/ardp.19893220508

Products guided by the article

Product name:Ethyl 2-(4-phenanthryl)propanoate

Cas No:122450-36-6

R&D Labs maybe for 122450-36-6

Lonzeal Pharmaceuticals Co., Ltd.

website:http://www.lonzeal.com

Contact:+86-13381011962

Address:RM 801, Yue MOMA, No. 26 Anningzhuang Rd. Haidian District, Beijing, China
Ningbo Distant Chemicals Co.,Ltd

Contact:86-574-27862490,27862438

Address:5F-3,#54 DaShaNi street,Ningbo,CHINA
Taiwan Surfactant Corp.

Contact:886 2 2541 0022

Address:8 Fl., No. 11, Sec. 1, Chung Shan North Rd., Taipei, Taiwan R.O.C.
Lonwin Chemical Group Limited

website:http://www.lonwinchem.com

Contact:Tel: 86-21-59858395

Address:No#966,Huaxu Road,Shanghai 201702,P.R.China
C-LAB Chemievermittlung GmbH

Contact:+49-9398-993127

Address:Untertorstr. 27

Relevant to this article

A convenient approach towards 2- and 3-aminobenzo[b]thiophenes

Doi:10.1016/j.tet.2010.01.069
(2010)
Design, synthesis and evaluation of 6-aryl-indenoisoquinolone derivatives dual targeting ERα and VEGFR-2 as anti-breast cancer agents

Doi:10.1016/j.ejmech.2016.04.029
(2016)
A straightforward and efficient catalyst-free one-pot synthesis of N-Acyl-1,3-diaryl-2-azaphenalene derivatives via multicomponent reactions

Doi:10.1246/cl.2010.180
(2010)
Practical Synthesis of α-Trifluoromethylated Pyridines Based on Regioselective Cobalt-Catalyzed [2+2+2] Cycloaddition using Trifluoromethylated Diynes with Nitriles

Doi:10.1002/adsc.202001433
(2021)
Chirality sensing of amines, diamines, amino acids, amino alcohols, and α-hydroxy acids with a single probe

Doi:10.1021/ja410428b
(2013)
A concise route to iboga-analogues via the formation of suitably substituted-2-indoles

Doi:10.1016/j.tetlet.2010.02.028
(2010)

Article Doi