Bohlmann-Rahtz cyclodehydration of aminodienones to pyridines using N-iodosuccinimide

DOI: 10.3390/molecules15053211

Source and publish data:

Molecules p. 3211 - 3227 (2010)

Update date:2022-07-29

Topics: Pyridines N-Iodosuccinimide

Authors:

Bagley, Mark C.

Glover, Christian

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Article abstract of DOI:10.3390/molecules15053211

Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N-iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2, 3,6-trisubstituted pyridines in high yield and with total regiocontrol.

Full text of DOI:10.3390/molecules15053211

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