Synthesis and in vitro antibacterial activity of some 1-(difluoromethoxyphenyl)quinolone-3-carboxylic acids

DOI: 10.1002/jps.2600780716

Source and publish data:

Journal of Pharmaceutical Sciences p. 585 - 588 (1989)

Update date:2022-07-30

Topics:

Authors:

Xiao Xiao

Krishnan

Lin Lin

Delos Santos

Kuck Kuck

Babine Babine

Lang Jr.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jps.2600780716

We report on the synthesis of N-1-phenylquinolones in which the difluoromethoxy moiety is utilized as a halogen replacement. The antibacterial activity is discussed with reference to N-1-halophenylquinolones.

Full text of DOI:10.1002/jps.2600780716

Products guided by the article

Product name:(Z)-3-(4-Difluoromethoxy-phenylamino)-2-(2,4,5-trifluoro-benzoyl)-acrylic acid ethyl ester

Cas No:122551-45-5

R&D Labs maybe for 122551-45-5

Zhengzhou Yuanli Biological Technology Co., Ltd.

Contact:+86-371-67897870/67897895

Address:No. 38, Qingyang Street, Zhengzhou, Henan, China
He Bei Shun Er Chemical Co., LTD.

Contact:86-0311-86996932/86860168

Address:No 18,North street
Wudi Reaction Pharma&Chemical Co.,Ltd.

website:http://www.ruixinchem.com/

Contact:86-543-2257986

Address:Xinhai Industrial Zone, Wudi County,Shandong Province,China.
MS( MAOSHENG )Chemical CO.,LTD

Contact:+86-519-82726678.82726378

Address:TAOXI INDUSTRY ZONE JINTAN
Xuzhou Tianrun Chemical Co.,Ltd

website:http://www.tianrunchem.cn

Contact:86-516-83832636

Address:fuxing road

Relevant to this article

Design, synthesis and evaluation of novel 2-thiophen-5-yl-3H-quinazolin-4-one analogues as inhibitors of transcription factors NF-k{cyrillic}B and AP-1 mediated transcriptional activation: Their possible utilization as anti-inflammatory and anti-cancer ag

Doi:10.1016/j.bmc.2010.01.007
(2010)
Palladium and half sandwich ruthenium(II) complexes of selenated and tellurated benzotriazoles: Synthesis, structural aspects and catalytic applications

Doi:10.1016/j.jorganchem.2009.11.009
(2010)
Silver tetrakis(hexafluoroisopropoxy)aluminate as hexafluoroisopropyl transfer reagent for the chlorine/hexafluoroisopropyl exchange in imino phosphanes

Doi:10.1016/j.jorganchem.2009.11.014
(2010)
Use of a robust dehydrogenase from an archael hyperthermophile in asymmetric catalysis-dynamic reductive kinetic resolution entry into (s)-profens

Doi:10.1021/ja910778p
(2010)
Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 Entry Inhibitors

Doi:10.1021/jm300265j
(2012)
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca²⁺/calmodulin-dependent kinase II

Doi:10.1016/j.ejmech.2016.03.045
(2016)

Article Doi