Synthesis and in vitro antibacterial activity of some 1-(difluoromethoxyphenyl)quinolone-3-carboxylic acids

DOI: 10.1002/jps.2600780716

Source and publish data:

Journal of Pharmaceutical Sciences p. 585 - 588 (1989)

Update date:2022-07-30

Topics:

Authors:

Xiao Xiao

Krishnan

Lin Lin

Delos Santos

Kuck Kuck

Babine Babine

Lang Jr.

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Article abstract of DOI:10.1002/jps.2600780716

We report on the synthesis of N-1-phenylquinolones in which the difluoromethoxy moiety is utilized as a halogen replacement. The antibacterial activity is discussed with reference to N-1-halophenylquinolones.

Full text of DOI:10.1002/jps.2600780716

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