π-Allyl palladium ring closure strategy for the synthesis of a 1β-methylcarbapenem intermediate

Article abstract of DOI:10.1016/0040-4039(95)00448-L

A new ring closure by π-allyl palladium methodology is utilized in the synthesis of a 1-β-methyl carbapenem intermediate from 2-acetoxy azetidinone in six steps (40% yield).