CYCLOPEPTIDE ALKALOID MODEL STUDIES. A TWO-STEP CONVERSION OF 5-AMINOISOXAZOLES TO AMINO ACID BIS-AMIDES

DOI: 10.1016/S0040-4039(00)82266-2

Source and publish data:

Tetrahedron Letters p. 6067 - 6070 (1988)

Update date:2022-08-05

Topics:

Authors:

Lipshutz, Bruce H.

Reuter, Deborah C.

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Article abstract of DOI:10.1016/S0040-4039(00)82266-2

Thermolyses of substituted 5-aminoisoxazoles, readily available from common starting materials, lead to azirines in good yields.Subsequent hydration affords bis-amide derivatives of amino acids.

Full text of DOI:10.1016/S0040-4039(00)82266-2

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