SYNTHESIS OF CLAVULONE DERIVATIVES. SELECTIVE CLEAVAGE OF ESTER BONDS IN CLAVULONE

DOI: 10.1246/cl.1989.157

Source and publish data:

Chemistry Letters p. 157 - 160 (1989)

Update date:2022-08-04

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Authors:

Iguchi, Kazuo

Kaneta, Soichiro

Nagaoka, Hiroto

Yamada, Yasuji

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Article abstract of DOI:10.1246/cl.1989.157

The clavulone derivatives (1-O-demethylclavulone II and 4-O-deacetylclavulone II) were synthesized from clavulone II (1) by selective enzymatic hydrolisis of 1 using porcin liver esterase (PLE) and orange peel acetylesterase, respectively.The derivative (

Full text of DOI:10.1246/cl.1989.157

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