ENZYMATIC RESOLUTION OF ENDO-BICYCLOHEPT-2-YL BUTYRATES AND RELATED COMPOUNDS: STERIC REQUIREMENTS IN THE BRIDGE-REGION

DOI: 10.1016/0040-4020(89)80096-1

Source and publish data:

Tetrahedron p. 673 - 680 (1989)

Update date:2022-08-05

Topics:

Authors:

Koenigsberger, K.

Faber, K.

Marschner, Ch.

Penn, G.

Baumgartner, P.

Griengl, H.

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Article abstract of DOI:10.1016/0040-4020(89)80096-1

Butyrates of endo-bicyclo<2.2.2>octanols and endo-bicyclo<2.2.1>heptan-2-ols, the letter bearing substituents of different size at C-7, were hydrolysed enzymatically using Candida cylindracea lipase.Steric factors were found to influence enantioselection:

Full text of DOI:10.1016/0040-4020(89)80096-1

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