Synthesis of 19,19,20,20,20-Pentadeuteriolipoxin A4 Methyl Ester and 19,19,20,20,20-Pentadeuterioarachidonic Acid. Agents for Use in the Quantitative Detection of Naturally Occurring Eicosanoids

DOI: 10.1021/jo00284a025

Source and publish data:

Journal of Organic Chemistry p. 5522 - 5527 (1989)

Update date:2022-08-04

Topics:

Authors:

Marron, B.E.

Spanevello, R.A.

Elisseou, M.E.

Serhan, C.N.

Nicolaou, K.C.

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Article abstract of DOI:10.1021/jo00284a025

19,19,20,20,20-Pentadeuteriolipoxin A₄ methyl ester (2) was synthesized from key intermediates 31 and 32. 19,19,20,20,20-Pentadeuterioarachidonic acid (1) and its methyl ester (24) were also synthesized by sequential coupling of intermediates 1

Full text of DOI:10.1021/jo00284a025

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