Synthesis of 19,19,20,20,20-Pentadeuteriolipoxin A4 Methyl Ester and 19,19,20,20,20-Pentadeuterioarachidonic Acid. Agents for Use in the Quantitative Detection of Naturally Occurring Eicosanoids

DOI: 10.1021/jo00284a025

Source and publish data:

Journal of Organic Chemistry p. 5522 - 5527 (1989)

Update date:2022-08-04

Topics:

Authors:

Marron, B.E.

Spanevello, R.A.

Elisseou, M.E.

Serhan, C.N.

Nicolaou, K.C.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00284a025

19,19,20,20,20-Pentadeuteriolipoxin A₄ methyl ester (2) was synthesized from key intermediates 31 and 32. 19,19,20,20,20-Pentadeuterioarachidonic acid (1) and its methyl ester (24) were also synthesized by sequential coupling of intermediates 1

Full text of DOI:10.1021/jo00284a025

Products guided by the article

Product name:Toluene-4-sulfonic acid 5-(tert-butyl-diphenyl-silanyloxy)-pent-2-ynyl ester

Cas No:123167-28-2

R&D Labs maybe for 123167-28-2

Improve Medical Technology(Nanxiong) Co., Ltd

Contact:86-751-3836997

Address:No.33, Pingan First Road, Fine Chemical Industry Base, Nanxiong City, Shaoguan, Guangdong, China
Yingkou Sanzheng Organic Chemical Co. Ltd.

Contact:+86-417-3638818

Address:25 Gengxinli Village, Daqing Road, Yingkou, Liaoning, China
HANGZHOU PANYU CHEMICAL CO.,LIMITED

Contact:+86-571-86578491

Address:Rm 605, NO.1870 Binsheng Road,Binjiang Dist, Hangzhou, China
Jintan City Mego Chemical Co., Ltd

Contact:+86-0519-82814387

Address:23# Dengguan Town, Jintan, Jiangsu Province, China
BIOS CHEMICALS

Contact:+33-5-34012600

Address:28 ZA des Pignès

Relevant to this article

Lead optimization of diarylpyrimidines as non-nucleoside inhibitors of HIV-1 reverse transcriptase

Doi:10.1002/cmdc.201000045
(2010)
Facile synthesis of enantiopure 4-substituted 2-hydroxy-4butyrolactones using a robust Fusarium lactonase

Doi:10.1002/adsc.200900628
(2009)
2,7-Pyrrolo[2,1-f][1,2,4]triazines as JAK2 inhibitors: Modification of target structure to minimize reactive metabolite formation

Doi:10.1016/j.bmcl.2011.10.032
(2011)
Synthesis of functionalized α-CF₃-α-aminophosphonates via Cu(I)-catalyzed 1,3-dipolar cycloaddition

Doi:10.1016/j.jfluchem.2009.12.003
(2010)
Chemoenzymatic Synthesis of Advanced Intermediates for Formal Total Syntheses of Tetrodotoxin

Doi:10.1002/anie.201804602
(2018)
(E)-4-(α-Halo-p-tolyl)-2-oxo-3-butenoic Acids Inhibit Yeast Pyruvate Decarboxylase by a Diversity of Mechanisms: Multiple Fate for the Thiamin-Bound Enamine Intermediate

Doi:10.1021/ja00206a019
(1989)

Article Doi