New α-amino phosphonic acid derivatives of vinblastine: Chemistry and antitumor activity

DOI: 10.1021/jm00111a012

Source and publish data:

Journal of Medicinal Chemistry p. 1998 - 2003 (1991)

Update date:2022-09-26

Topics:

Authors:

Lavielle

Hautefaye

Schaeffer

Boutin Boutin

Cudennec

Pierre Pierre

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00111a012

A series of new amino phosphonic acid derivatives of vinblastine (1, VLB) has been synthesized and tested in vitro and in vivo for antitumor activity. The compounds were obtained from O⁴-deacetyl-VLB azide (5). All of the new products studied w

Full text of DOI:10.1021/jm00111a012

Products guided by the article

Product name:C₅₅H₇₂N₅O₁₀P

Cas No:123286-08-8

R&D Labs maybe for 123286-08-8

Nanjing Zelang Medical Technology Co. Ltd

Contact:86-25-83063290/13770714480

Address:Ganjiabian 108# 01 Unit,701-702 room,Yao Hua Street,Qixia District,Nanjing,Jiangsu,China
Shenzhen Sungening Medicine Co., Ltd

Contact:+86-871-65110906

Address:Room702, Building 2, 365 Dianchi Road, Kunming, Yunnan Province, P.R. China
Lanzhou SchiffChem Co.,Ltd

Contact:86-931-8272767

Address:Room 602, No.461, Nanchang Road, Chengguan District, Lanzhou City, China PRC
Qingdao Kingway Pharmtech Co., Ltd.

Contact:86-532-87118899

Address:No. 88, Middle Haixi Road, Jiaonan City, Qingdao, China
Ningbo Tide Imp. & Exp. Co., Ltd.

Contact:+86-571-8993 7933; +86-571-8993 6453

Address:7/F Anno Domini Building, Tower South, 8 Qiu Shi Road,Hangzhou,China.

Relevant to this article

Organocatalytic peroxidation of malonates, β-ketoesters, and cyanoacetic esters using n-Bu₄NI/t-BuOOH-mediated intermolecular oxidative C(sp³)-O coupling

Doi:10.1016/j.tet.2015.09.047
(2015)
Potent antagonist for the vitamin D receptor: Vitamin D analogues with simple side chain structure

Doi:10.1021/jm100649d
(2010)
C-glycosyl juglone in angucycline synthesis: Total synthesis of galtamycinone, common aglycon of C-glycosyl naphthacenequinone-type angucyclines

Doi:10.1016/S0040-4020(97)01034-X
(1997)
Intramolecular [1 + 4 + 1] cycloaddition: Establishment of the method

Doi:10.1021/ja103551x
(2010)
5-C ₅Me₅)M[N(i-Pr)C(Me)N(i-Pr)]}₂(μ- η¹:η¹-N₂) (M = Mo and W)">Dinitrogen complexation and extent of N-N activation within the group 6 "End-On-Bridged" dinuclear complexes, {(η⁵-C ₅Me₅)M[N(i-Pr)C(Me)N(i-Pr)]}₂(μ- η¹:η¹-N₂) (M = Mo and W)

Doi:10.1021/ja100469f
(2010)
Development of supramolecular organo-gel based on tripeptide skeletons

Doi:10.1248/cpb.58.680
(2010)

Article Doi