New α-amino phosphonic acid derivatives of vinblastine: Chemistry and antitumor activity

DOI: 10.1021/jm00111a012

Source and publish data:

Journal of Medicinal Chemistry p. 1998 - 2003 (1991)

Update date:2022-09-26

Topics:

Authors:

Lavielle

Hautefaye

Schaeffer

Boutin Boutin

Cudennec

Pierre Pierre

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00111a012

A series of new amino phosphonic acid derivatives of vinblastine (1, VLB) has been synthesized and tested in vitro and in vivo for antitumor activity. The compounds were obtained from O⁴-deacetyl-VLB azide (5). All of the new products studied w

Full text of DOI:10.1021/jm00111a012

Products guided by the article

Product name:C₅₅H₇₂N₅O₁₀P

Cas No:123286-08-8

R&D Labs maybe for 123286-08-8

ZHANGJIAGANG FREE TRADE ZONE YONG HAN INTERNATIONAL TRADING CO., LTD(expird)

Contact:86 512 57910558

Address:qianjin M road
SPE Chemicals Co.,Ltd

Contact:

Address:ROOM 1715, No#345 Jin Xiang Road, Pudong District
Shandong Hongxiang Zinc Co., Ltd

Contact:086-0311-66187879

Address:DaWang developing zone
ZHEJIANG JIANYE CHEMICAL CO.,LTD.

Contact:86-571-64149273,64149234

Address:No. 48, Fuxi Road, Meicheng Town
uni source industries limited

Contact:86 21 3772 9386

Address:Rm.1803,Starry Bldg.1,1505 Meijiabang Road,Shanghai 201620 China

Relevant to this article

Organocatalytic peroxidation of malonates, β-ketoesters, and cyanoacetic esters using n-Bu₄NI/t-BuOOH-mediated intermolecular oxidative C(sp³)-O coupling

Doi:10.1016/j.tet.2015.09.047
(2015)
Potent antagonist for the vitamin D receptor: Vitamin D analogues with simple side chain structure

Doi:10.1021/jm100649d
(2010)
C-glycosyl juglone in angucycline synthesis: Total synthesis of galtamycinone, common aglycon of C-glycosyl naphthacenequinone-type angucyclines

Doi:10.1016/S0040-4020(97)01034-X
(1997)
Intramolecular [1 + 4 + 1] cycloaddition: Establishment of the method

Doi:10.1021/ja103551x
(2010)
5-C ₅Me₅)M[N(i-Pr)C(Me)N(i-Pr)]}₂(μ- η¹:η¹-N₂) (M = Mo and W)">Dinitrogen complexation and extent of N-N activation within the group 6 "End-On-Bridged" dinuclear complexes, {(η⁵-C ₅Me₅)M[N(i-Pr)C(Me)N(i-Pr)]}₂(μ- η¹:η¹-N₂) (M = Mo and W)

Doi:10.1021/ja100469f
(2010)
Development of supramolecular organo-gel based on tripeptide skeletons

Doi:10.1248/cpb.58.680
(2010)

Article Doi