'Click chemistry' synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase

DOI: 10.1016/j.bmc.2010.02.053

Source and publish data:

Bioorganic and Medicinal Chemistry p. 2412 - 2427 (2010)

Update date:2022-08-02

Topics:

Authors:

Carvalho, Ivone

Andrade, Peterson

Campo, Vanessa L.

Guedes, Paulo M.M.

Sesti-Costa, Renata

Silva, Jo?o S.

Schenkman, Sergio

Dedola, Simone

Hill, Lionel

Rejzek, Martin

Nepogodiev, Sergey A.

Field, Robert A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.bmc.2010.02.053

Trypanosoma cruzi trans-sialidase (TcTS) plays a key role in the recognition and invasion of host cells and in enabling the parasite to escape the human immune response. To explore this potential drug target, we have synthesized a small library of substra

Full text of DOI:10.1016/j.bmc.2010.02.053

Products guided by the article

Product name:C₂₂H₂₆N₄O₉

Cas No:1233043-56-5

R&D Labs maybe for 1233043-56-5

SHENYANG COMEBOARD TECHNOLOGY CO., LTD

Contact:+86-24-25724626

Address:Room2210,Tianbao International Building,No.8-1 Weigong South Street,Tiexi District,Shenyang,China
chemonlinephramacistdepot

Contact:86-607-68073220

Address:1 ave na road jiahua st
TIANJIN FESTO CHEMICAL CO.,LTD(expird)

Contact:86-22-25814570

Address:No.12th,5th Ave.,TEDA,Tianjin,China
Suzhou CarbonWell Pharma-Tech Co., Ltd

Contact:Tel: + 86 (0)512-8898-1216; + 86-18606258602

Address:2358 Changan Road, Wujiang Scientific Innovation Park, Wujiang, Jiangsu Province, P. R. China 215200
Taimai Sanluck Pharmaceutical Co.,Ltd

Contact:86-592-7662921

Address:8D,No.186,Huarong Road,Huli,Xiamen,China

Relevant to this article

Cyclization of chalcones to isoxazole and pyrazole derivatives

Doi:10.1007/s10593-010-0455-8
(2009)
Ortho-selectivity in S_NAr substitutions of 2,4-dihaloaromatic compounds. Reactions with anionic nucleophiles

Doi:10.1016/j.tetlet.2010.03.124
(2010)
A chiral synthesis of trans-carbapenam-3-carboxylic acid and the assignment of (3S,5S) configuration to the corresponding product from Serratia and Erwinia species

Doi:10.1039/c39890000423
(1989)
MODELS OF FOLATE COFACTORS 20. AN APPROACH TO DEETHYLEBURNAMONINE

Doi:10.1016/0040-4020(89)80116-4
(1989)
Redox properties and cytotoxicity of synthetic isomeric mitochondriotropic derivatives of the natural polyphenol quercetin

Doi:10.1002/ejoc.201100573
(2011)
Nano- and microstructure fabrication by using a three-component system

Doi:10.1002/chem.200903256
(2010)

Article Doi