MODELS OF FOLATE COFACTORS 20. AN APPROACH TO DEETHYLEBURNAMONINE

Article abstract of DOI:10.1016/0040-4020(89)80116-4

The substituted 5,10-methylenetetrahydrofolate model (3a) derived from addition of the dianion of dimethyl 2-methoxycarbonylglutarate to 1,5,5-trimethyl-3-tosyl-1-imidazolidinium iodide (1) transfers a 7-carbon functionalized fragment to tryptamine to yie