An Optically Active Terpenic Synthon for Δ9-Cannabinoids: Synthesis of (-)-11-Hydroxy-Δ9-tetrahydrocannabinol (THC) and Its 1'.1'-Dimethylheptyl Analogue

DOI: 10.1021/jo00284a011

Source and publish data:

Journal of Organic Chemistry p. 5428 - 5430 (1989)

Update date:2022-08-05

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Authors:

Siegel, Craig

Gordon, Patrick M.

Razdan, Raj K.

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Article abstract of DOI:10.1021/jo00284a011

A facile entry into Δ⁹-tetrahydrocannabinoids has been achieved via synthon 1, synthesized from (R)-(+)-perillaldehyde in a six-step process (23percent overall yield).

Full text of DOI:10.1021/jo00284a011

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