Asymmetric N–H insertion reaction with chiral aminoalcohol as catalytic core of Cinchona alkaloids

DOI: 10.1248/cpb.c18-00795

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 393 - 396 (2019)

Update date:2022-07-29

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Authors:

Shinohara, Hideyuki

Saito, Hiroaki

Uchiyama, Taketo

Miyake, Muneharu

Miyairi, Shinichi

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Article abstract of DOI:10.1248/cpb.c18-00795

In order to develop an efficient organocatalyst for the enantioselective N–H insertion reaction via carbene/carbenoid, the catalytic core of the cinchona alkaloids was investigated. According to our working hypothesis of an eight-membered ring transition

Full text of DOI:10.1248/cpb.c18-00795

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