Reversible Inhibitors of the Gastric (H+/K+)-ATPase. 1. 1-Aryl-4-methylpyrroloquinolines as Conformationally Restrained Analogues of 4-(Arylamino)quinolines

DOI: 10.1021/jm00164a010

Source and publish data:

Journal of Medicinal Chemistry p. 527 - 533 (1990)

Update date:2022-09-26

Topics:

Authors:

Brown, Thomas H.

Ife, Robert J.

Keeling, David J.

Laing, Shiona M.

Leach, Colin A.

et al. et al.

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Article abstract of DOI:10.1021/jm00164a010

The 4-(arylamino)quinoline 4, previously described as an antiulcer compound, is shown to be an inhibitor of the gastric (H⁺/K⁺)-ATPase.It is postulated that 1-arylpyrrolo<3,2-c>quinolines 6 act as conformationally restrained analogue

Full text of DOI:10.1021/jm00164a010

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