1,2,4-Diazaphosphole Nucleosides. Synthesis, Structure, and Antitumor Activity of Nucleosides with a λ3 Phosphorus Atom

DOI: 10.1021/jm00164a016

Source and publish data:

Journal of Medicinal Chemistry p. 572 - 576 (1990)

Update date:2022-09-26

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Authors:

Riley, Timothy A.

Larson, Steven B.

Avery, Thomas L.

Finch, Rick A.

Robins, Roland K.

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Article abstract of DOI:10.1021/jm00164a016

Glycosylation of 1,2,4λ³-diazaphosphole (4) under Lewis acid catalyzed conditions gave 1-α-D-ribofuranosyl-1,2,4λ³-diazaphosphole (5) as the only product.Ethyl 1,2,4λ³-diazaphosphole-3-carboxylate (10) was synthesized by t

Full text of DOI:10.1021/jm00164a016

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