
Bioorganic and Medicinal Chemistry Letters p. 3636 - 3639 (2010)
Update date:2022-07-29
Topics:
Li, Tao
Bunnelle, William H.
Ryther, Keith B.
Anderson, David J.
Malysz, John
Helfrich, Rosalind
Gronlien, Jens H.
Hkerud, Monika
Peters, Dan
Schrimpf, Michael R.
Gopalakrishnan, Murali
Ji, Jianguo
Biaryl substituted 2,5-diazabicyclo[2.2.1]heptanes have been synthesized and tested for their affinity toward α7 neuronal nicotinic receptors (NNRs). SAR studies established that 5-N-methyl substituent, heteroaryl linker and the nature of terminal aryl gr
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Doi:10.1039/d1ra00732g
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