
Tetrahedron Letters p. 3811 - 3812 (1989)
Update date:2022-07-29
Topics:
Itoh, Toshiyuki
Takagi, Yumiko
Fujisawa, Tamotsu
A novel carbon-carbon bond formation, i.e. ethylation at the α-position of the nitrile was occurred in the bakers' yeast reduction of cyanoacetone, to give optically pure (3S)-3-hydroxy-2-ethylbutyronitrile.
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