
Tetrahedron Letters p. 1369 - 1372 (1989)
Update date:2022-08-04
Topics:
Cazaux, Louis
Duriez, Marie-Christine
Picard, Claude
Tisnes, Pierre
Two new 18-membered tetralactams with two dimethyleneoxy moieties are synthesized by direct macrocyclization or steps reaction.In the latter case symmetrical or unsymmetrical compounds can be obtained.The unsymmetrical tetralactam shows a very high selectivity for barium vs.Na+ and Zn2+ and to a lesser extent vs.K+, Mg2+ and Ca2+ in the extraction procedure with picrates.In addition, the stability constants are determined for the two 1:1 tetralactam:Ba2+ complexes by UV spectrophotometry in THF solution.
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