4-Alkyl-1,4-dihydropyridines Derivatives as Specific PAF-Acether Antagonists

DOI: 10.1021/jm00174a017

Source and publish data:

Journal of Medicinal Chemistry p. 3205 - 3210 (1990)

Update date:2022-09-26

Topics:

Authors:

Sunkel, Carlos E.

Casa-Juana, Miguel Fau de

Santos, Luis

Gomez, M. Mar

Villarroya, Mercedes

et al. et al.

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Article abstract of DOI:10.1021/jm00174a017

A new series of 4-alkyl-1,4-dihydropyridines (1,4-DHP) were synthesized and evaluated for their ability to inhibit washed rabbit platelet aggregation induced by PAF-acether (1-O-hexadecyl/octadecyl-2-O-acetyl-sn-glycero-3-phosphorylcholine) and to reverse

Full text of DOI:10.1021/jm00174a017

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