Tetrahedron p. 6309 - 6318 (1989)
Update date:2022-07-30
Topics:
Baldwin, Jack E.
Moloney, Mark G.
North, Michael
Treatment of α-t-butyl β-methyl N-Z-(S)-aspartate (2) with lithium amide bases generates the corresponding β-ester enolate, which can be alkylated with suitable electrophiles.The application of this strategy for synthesis of optically active amino acids h
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