A microbially-based approach for the synthesis of chiral secondary alcohols bearing the difluoromethyl or chlorodifluoromethyl group

DOI: 10.1016/S0022-1139(00)81174-4

Source and publish data:

Journal of Fluorine Chemistry p. 271 - 284 (1992)

Update date:2022-07-30

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Authors:

Kitazume, Tomoya

Asai, Masatomo

Tsukamoto, Takashi

Yamazaki, Takashi

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Article abstract of DOI:10.1016/S0022-1139(00)81174-4

A synthetic approach to both enantiomers of the secondary alcohols , involving the stereoselective hydrolysis of ester derivatives, is described.The absolute configurations of these difluoromethylated or chlorodifluoromethylated molecules were determined.

Full text of DOI:10.1016/S0022-1139(00)81174-4

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