An Improved Method for the Preparation of Symmetrically Substituted Porphyrins via 2-Methoxymethyl-3,4-disubstituted Pyrrole Derivatives

Article abstract of DOI:10.1246/cl.1989.1107

2-Methoxymethylpyrrole derivatives readily available from 2-methylthiomethylpyrroles were found to be readily cyclized to porphyrinogens with formic acid, and subsequent oxidation with O2 affords the corresponding porphyrins in excellent yields.