Synthesis, antinociceptive activity and opioid receptor profiles of 3-(0ctahydro-1H-pyrano- And -thiopyrano[4,3-c]pyridin-8a-yl)phenols

DOI: 10.1039/P19890001177

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 1177 - 1186 (1989)

Update date:2022-08-05

Topics:

Authors:

Bays, David E.

Brown, Dearg S.

Belton, David J.

Lloyd, Jane E.

McElroy, Andrew B.

Meerholz, Clive A.

Scopes, David I. C.

Birch, Phillip J.

Hayes, Ann G.

Sheehan, Michael J.

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Article abstract of DOI:10.1039/P19890001177

The synthesis of a series of novel cis- and trans-3-(octahydro-1H-pyrano[4, 3-c]pyridin-8a-yl)-phenols (13a - 1), (15a, b), (20a - d), (21a-e) and the trans-3-(octahydro-1H-thiopyrano[4,3-c]-pyridin-8a-yl)phenol (26) is described. Alkylation of 1 -methyl-

Full text of DOI:10.1039/P19890001177

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