Palladium-Catalyzed Synthesis of trans-2,5-Diaryltetrahydrofurans, Potent Platelet-Activating Factor Antagonists

DOI: 10.1021/jo00289a002

Source and publish data:

Journal of Organic Chemistry p. 407 - 408 (1990)

Update date:2022-09-26

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Authors:

Larock, Richard

Gong, William H.

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Article abstract of DOI:10.1021/jo00289a002

trans-2,5-Diaryltetrahydrofurans 1-3, potent platelet-activating factor antagonists, have been synthesized regio- and stereoselectively by a three-step approach involving sequential palladium-catalyzed diarylation of 2,3-dihydrofuran and subsequent hydrog

Full text of DOI:10.1021/jo00289a002

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