Journal of Medicinal Chemistry p. 286 - 291 (1990)
Update date:2022-08-05
Topics:
Halfpenny
Horwell
Hughes
Hunter
Rees
This paper describes the chemical synthesis, μ/κ opioid receptor selectivity and analgesic activity of 14 novel N-[2-(1-pyrrolidinyl)-4- or -5-substituted-cyclohexyl]arylacetamide derivatives. The prototype κ-selective agonist, PD117302 (trans-N-methyl-N-
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(1988)Doi:10.1134/S1070428008090145
(2008)Doi:10.1016/S0022-1139(00)81994-6
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