Synthesis of 3-Substituted 2,5-Dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxyl Radicals, Useful for Spin-Labelling of Biomolecules

Article abstract of DOI:10.1055/s-1989-27306

Synthesis and some reactions of 3-substituted 2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxyl radicals (nitroxyl radicals, nitroxides) activated with carbonyl, cyano, or ester electron-withdrawing groups have been described.These compounds are useful new SH-reagents for spin-labelling of biomolecules.