Novel antagonists of the 5-HT3 receptor. Synthesis and structure-activity relationships of (2-alkoxybenzoyl)ureas

DOI: 10.1021/jm00087a003

Source and publish data:

Journal of Medicinal Chemistry p. 1515 - 1520 (1992)

Update date:2022-08-03

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Authors:

Bradley Bradley

Ward Ward

White White

Coleman Coleman

Taylor Taylor

Rhodes Rhodes

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Article abstract of DOI:10.1021/jm00087a003

A series of benzoylureas derived from bicycle amines were prepared and evaluated for 5-HT₃ antagonist activity on the rat isolated vagus nerve. From among these compounds, those analogues which were ortho substituted by an alkoxy group on the b

Full text of DOI:10.1021/jm00087a003

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