
Tetrahedron Letters p. 2153 - 2156 (1989)
Update date:2022-07-29
Topics:
Thijs, L.
Egenberger, D. M.
Zwanenburg, B.
A total synthesis of the twelve-membered ring lactone Patulolide C is described.The essentials of this synthesis are: nucleophilic ring opening of R-methyloxirane with a lithium acetylide, a Sharpless epoxidation, strategic use of the photochemical rearra
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