C-10 DIPEPTIDE DERIVATIVES OF COLCHICINE

Article abstract of DOI:10.1007/BF00596708

The methyl esters of colchicidylglycyl-L-leucine, -L-phenylalanine, and -L-tryptophan and the ethyl esters of colchicidylglycylglycine, -L-isoleucine, -L-valine, -L-tyrosine, amd -L-glutamic acid have been obtained by the condensation of colchicidylglycine and esters of amino acids.The structures of the compounds have been confirmed on the basis of their UV spectra and nuclear magnetic resonance spectra.