Tetrahedron Letters p. 2801 - 2804 (1989)
Update date:2022-07-29
Topics:
Jegham, Samir
Das, Bhupesh C.
A new route to optically pure cis- and trans-2,5-disubstituted pyrrolidines is described and is illustrated by the enantiospecific synthesis of (2R,5S)-(+)-2-ethyl-5-heptylpyrrolidine 9 and (2R,5R)-(-)-2-ethyl-5-heptylpyrrolidine 10 starting from (R)-(-)-2-amino-1-butanol 1.
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