
Tetrahedron Letters p. 1675 - 1678 (1989)
Update date:2022-08-02
Topics:
Takle, Andrew
Kocienski, Philip
A convergent synthesis of Lacrimin A (2) is described in which a Wadsworth-Emmons reaction was used to constract the C10-C11 double bond and link the isochroman-1-one phosphonate (4) to the spiroacetal aldehyde (3).
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