Allylic Stereocenter Directed Asymmetric Conjugate Addition. Enantioselective Synthesis of 3-Alkylsuccinaldehydic Acid Methyl Esters

DOI: 10.1021/jo00375a064

Source and publish data:

Journal of Organic Chemistry p. 5041 - 5043 (1986)

Update date:2022-08-05

Topics:

Authors:

Bernardi, Anna

Cardani, Silvia

Poli, Giovanni

Scolastico, Carlo

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Article abstract of DOI:10.1021/jo00375a064

Cuprate reagents add to ester 2 with excellent ?-face selectivity (>=95:5) and furnish the title compounds in high enantiomeric excess after removal of the chiral auxiliary.

Full text of DOI:10.1021/jo00375a064

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