Total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a unique putreanine trimer and putreanine tetramer acylpolyamine chain

DOI: 10.1016/S0040-4039(98)01379-3

Source and publish data:

Tetrahedron Letters p. 6479 - 6482 (1998)

Update date:2022-08-05

Topics:

Authors:

Saito, Hiroaki

Yuri, Etsuko

Miyazawa, Masahiro

Itagaki, Yasuhiro

Nakajima, Terumi

Miyashita, Masaaki

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Article abstract of DOI:10.1016/S0040-4039(98)01379-3

The first total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a 4-hydroxyindole nucleus and a unique putreanine trimer and tetramer acylpolyamine chain, respectively, has been achieved by the iterative use of a key azide compound.

Full text of DOI:10.1016/S0040-4039(98)01379-3

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