USE OF HEXAMETHYLPHOSPHORAMIDE (HMPA) IN THE ALKYLATION OF AROMATIC AMINES: SYNTHESIS OF AZETIDINES, PYRROLIDINES, PIPERIDINES AND HEXAHYDROAZEPINES

DOI: 10.1016/0040-4020(89)80091-2

Source and publish data:

Tetrahedron p. 629 - 636 (1989)

Update date:2022-07-30

Topics:

Authors:

Juaristi, Eusebio

Madrigal, Domingo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4020(89)80091-2

The direct alkylation of p-toluidine, as a model of aromatic amines, with 1,3-, 1,4-, 1,5- and 1,6-ditosylates, -dibromides or -dimesitylates in HMPA as solvent affords the corresponding cyclic amines.The convenience of this reaction and some observed lim

Full text of DOI:10.1016/0040-4020(89)80091-2

Products guided by the article

Product name:N,N',N'',N'''-tetrakis(p-tolyl)1,5,9,13-tetraazacyclohexadecane

Cas No:125836-34-2

R&D Labs maybe for 125836-34-2

Hangzhou innopharma technology Co,.Ltd.(expird)

Contact:+86-13388601988

Address:Room845,lixin building, moganshan road, hangzhou, china
Haitong Chemical Industrial Co.,Ltd.

website:https://www.haitonglongwin.com/

Contact:+86-022-66221018

Address:18-701, No.99, The 4th Street, TEDA,
Jinan Hongfangde Pharmatech Co.LTD

Contact:0531-88870908

Address:F Bldg,750#,Shunhua Rd,New&High-tech Zone,Jinan,Shandong,China 250101
SHANDONG QINGYUNCHANGXIN CHEMICAL SCIENCE-TECH CO.,LTD

Contact:86-21-60560171

Address:1689Donghuan Rade,Qingyun County, Dezhou City, Shandong,China
BAODING SINO-CHEM INDUSTRY CO.,LTD

Contact:0312-5956088

Address:NO.8 FUXING ROAD,CHINA

Relevant to this article

Unusually large bite angle of a distally diphosphanylated calix[4]arene chelator

Doi:10.1002/ejic.201000595
(2010)
Regioselective synthesis of poly-substituted naphthalenes via a Pd-catalyzed cyclization of modified Baylis-Hillman adducts: Selective 6-endo Heck reaction and an aerobic oxidation cascade

Doi:10.1016/j.tetlet.2010.09.127
(2010)
N-Methylacridinium Salts: Carbon Lewis Acids in Frustrated Lewis Pairs for σ-Bond Activation and Catalytic Reductions

Doi:10.1002/anie.201406122
(2014)
Activation of an aryl C-H bond converts chelating diphenolate ligands bound to zirconium into trianionic pincer ligands: σ-Donor ligand effects versus thermolysis

Doi:10.1021/om100732d
(2010)
Convenient and easy access to 2-hydroxycyclopent-2-enones from acylcyanohydrins

Doi:10.1016/j.tet.2019.07.010
(2019)
Study on the reactions of 3-bromo-4-ethoxy-1,1,1-trifluoro-3-buten-2-one with benzenethiols promoted by InCl₃?4H₂O

Doi:10.1002/cjoc.201090275
(2010)

Article Doi