Synthesis p. 638 - 641 (1989)
Update date:2022-09-26
Topics:
Lee, Kee-Jung
Kim, Seongkon
Um, Hyunsuk
Park, Hokoon
A novel method for the synthesis of 8-oxo-3-thioxo-2,3,7,8-tetrahydro-1,2,4-triazolo<4,3-a>pyrazines 3 consists of an intramolecular condensation reaction of substituted 1,2,4-triazoline-3-thiones 9, which possess acetal and aminocarbonyl moieties, with 5 percent hydrochloric acid.This method is convenient by virtue of its simplicity and the good yields.
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Doi:10.1002/ejoc.201000984
(2010)Doi:10.1139/V10-091
(2010)Doi:10.1080/10426501003598614
(2010)Doi:10.1248/cpb.37.2995
(1989)Doi:10.1002/jhet.474
(2010)Doi:10.1039/c7ob00240h
(2017)
