An SN2′ displacement approach to allenyl acetates

DOI: 10.1016/j.tetlet.2010.10.013

Source and publish data:

Tetrahedron Letters p. 6454 - 6456 (2010)

Update date:2022-09-26

Topics:

Authors:

Asikainen, Martta

Lewis, William

Blake, Alexander J.

Woodward, Simon

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.tetlet.2010.10.013

Reaction of cuprates derived from R³MgBr/CuI/LiBr (R³ = n-alkyl) with R¹CCCH(O₂CR²)₂ (R¹ = sp² hybridised substituent, R² = mainly Me, alkyl, Ph) provides access to allenyl esters R¹R ³CCCH(O₂CR²) (51-88%). Such species are not accessible via rearrangement of precursor propargylic R¹R ³C(O₂CR²)CCH.

Full text of DOI:10.1016/j.tetlet.2010.10.013

Products guided by the article

Product name:3-(4-methoxyphenyl)prop-2-yne-1,1-diyl diacetate

Cas No:1260421-82-6

R&D Labs maybe for 1260421-82-6

waho int'l company

Contact:+86-579-85206992

Address:No 451 chouzhou north road ,room 1106 int'l business center , yiwu ,china
Shenyang Mole pharmaceutical Technology Development Co.,Ltd

Contact:+86-24-31204918/13889278616

Address:No.44, wanliutang road, shenhe District of Shenyang
Qingdao XinYongAn Chemicals Co., Ltd

Contact:+86-532-81107967

Address:Chengyang dual-port industrial park by the sea，Qingdao
Shanghai Apeptide Co., Ltd.

website:http://www.apeptides.com/en/

Contact:+86-21-60871011

Address:No. 80 Chuanshan Shuyuan Steet,Pudong,Shanghai
Shandong Topscience Biotech Co., Ltd.

Contact:0633-2619278

Address:No. 98 Lanshan West Road, Lanshan District, Rizhao, Shandong Province, P.R. of China

Relevant to this article

A CONVENIENT SYNTHETIC ACCESS TO &β,&β-DIFLUORO-&γ-KETO-&α-AMINO ACIDS. APPLICATION TO THE SYNTHESIS OF A POTENTIAL INHIBITOR OF KYNURENINASE

Doi:10.1016/S0040-4039(01)80471-8
(1989)
Chemoselective synthesis of functionalized 2,5-dihydro-2-thioxo-1H- imidazoles from 5,5-diarylthiohydantoins and activated acetylenes

Doi:10.1080/10426501003752179
(2010)
Enantioselective cyclopropanation reactions with planar-chiral pyridinium ylides: A substituent effect and a remote steric effect

Doi:10.1002/adsc.201000079
(2010)
Copper-Catalyzed C(sp³)-S Bond and C(sp²)-S Bond Cross-Coupling of 2-(2-Iodobenzoyl) Substituted or 2-(2-Iodobenzyl) Substituted 1,2,3,4-Tetrahydroisoquinolines with Potassium Sulfide: Synthesis of Isoquinoline-Fused 1,3-Benzothiazine Scaffolds

Doi:10.1021/acs.joc.6b02943
(2017)
Scaffold hopping in discovery of HIV-1 non-nucleoside reverse transcriptase inhibitors: From CH(CN)-DABOs to CH(CN)-dapys

Doi:10.3390/molecules25071581
(2020)
Hydrogen storage in a highly interpenetrated and partially fluorinated metal-organic framework

Doi:10.1021/ic101153c
(2011)

Article Doi