SYNTHESIS OF A BIOTIN CONJUGATE OF THE PCP ANALOGUE "METHAPHIT FOR POTENTIAL USE IN NMDA/PCP RECEPTOR ISOLATION

DOI: 10.1016/S0040-4039(01)80756-5

Source and publish data:

Tetrahedron Letters p. 4613 - 4616 (1989)

Update date:2022-08-03

Topics:

Authors:

Kozlowski, Alan P.

Tueckmantel, Werner

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Article abstract of DOI:10.1016/S0040-4039(01)80756-5

A high yielding synthesis of a biotinylated analogue 2 of methaphit for possible use in NMDA/PCP receptor isolation is reported.The inability of this agent to displace <³H>MK-801 binding is interpreted in terms of the physical location of the P

Full text of DOI:10.1016/S0040-4039(01)80756-5

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