BIS(ALLYLOXY)(DIISOPROPYLAMINO)PHOSPHINE AS A NEW PHOSPHINYLATION REAGENT FOR THE PHOSPHORYLATION OF HYDROXY FUNCTIONS

Article abstract of DOI:10.1016/S0040-4039(01)80694-8

Bis(allyloxy)(diisopropylamino)phosphine is a new phosphinylating agent which can be employed for an effective phosphorylation of hydroxy functions after activation by tetrazole followed by an oxidation step.The allyl protecting groups are removed afterwards with Pd(O)P(C6H5)3)4 leading to the corresponding phophorylated substrate.