New methodology for the synthesis of 3-substituted coumarins via palladium-catalyzed site-selective cross-coupling reactions

Article abstract of DOI:10.1055/s-0030-1259014

A particularly useful, easy, and concise synthesis of diversified 3-aryl coumarin was achieved using Heck coupling reactions between coumarin and aryliodides. The introduction of the aryl moiety occurred regioselective at the 3-position of the heteroaromatic ring. Georg Thieme Verlag Stuttgart - New YorK.