A Mild Procedure for the Selective Formation of Aryl Ethers and Triaryl Diethers using Arene-M-Cp Cations (M=Fe, Ru; Cp=η5-cyclopentadienyl)

Article abstract of DOI:10.1039/c39890001363

Reaction of (η⁶-1,3-dichlorobenzene)(η⁵-cyclopentadienyl)iron hexafluorophosphate with aryl oxides from protected tyrosines proceeds under mild conditions to generate aryl ethers, and the halogens may be displaced sequentially, allowing the preparation of unsymmetrical or symmetrical triaryl diethers; (η⁶-N-acetyl-4-chlorophenylalanine methyl ester)(η⁵-cyclopentadienyl)ruthenium hexafluorophosphate was prepared and was shown to react with protected tyrosine aryl oxide to generate dityrosine derivatives, and a mild photochemical method for demetallation of the arene-M-Cp (Cp=η⁵-cyclopentadienyl)complexes is descrided.

Full text of DOI:10.1039/c39890001363

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online