Tetrahedron Letters p. 4795 - 4798 (1989)
Update date:2022-08-03
Topics:
Chen, Gu Huai
Hoechstetter, Craig
Knochel, Paul
The mixed copper, zinc benzylic organometallics 1a-1c react efficiently with various electrophiles.By the reaction with acylchlorides, highly functionalized 2-substituted indoles are produced.The treatment of 1a with allylic bromides, 3-iodo-cyclohexenone and ethyl propiolate furnishes polyfunctionalized anilines.Several of them could be converted into five or seven-membered heterocycles.
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Doi:10.1021/ic102204h
(2011)Doi:10.1021/acs.orglett.5b02185
(2015)Doi:10.3390/molecules16010298
(2011)Doi:10.1016/j.bmcl.2010.12.059
(2011)Doi:10.1016/S0040-4039(01)80676-6
(1989)Doi:10.1007/BF00808773
(1989)
